Molecular Diagnostics Coordination

PD Dr. rer. nat. Irina Bonzheim

Head of Molecular Pathology Diagnostics, Tübingen University Hospital Expert in Hematopathology & Molecular Lymphoma Diagnostics

Short biography & role in the DECODE VRL study

PD Dr. Irina Bonzheim is a renowned molecular pathologist with a focus on hematopathology and genetic tumor analysis. She heads molecular diagnostics at the Institute of Pathology and Neuropathology, Tübingen University Hospital and is significantly involved in the molecular genetic investigation of malignant lymphoma.

In the DECODE VRL study, she coordinates molecular diagnostics for vitreoretinal lymphoma (VRL). Her laboratory specifically analyses genetic markers such as MYD88 L265P, miRNA profiles and epigenetic changes in order to develop new standardized diagnostic methods.

Scientific & clinical career

  • Since 2014: Head of Molecular Pathology Diagnostics, Tübingen University Hospital
  • Since 2008: Postdoc & Hematopathology Researcher, Tübingen University Hospital
  • 2007 — 2008: Postdoc at Helmholtz Center Munich
  • 2003 — 2007: Doctoral thesis in hematopathology, University of Würzburg
  • 1997 — 2002: Diploma degree in biology, Ulm University

Dr. Bonzheim has written over 100 scientific publications and is active in international research networks as a specialist in molecular diagnostics. Research Priorities & Participation in the DECODE VRL Study

  • Molecular genetic diagnostics for VRL: analysis of MYD88 mutations, miRNA profiles, and clonal B-cell rearrangements
  • Genetics of Malignant Lymphomas: Investigation of Genetic & Epigenetic Mechanisms to Improve Diagnostics
  • Development of new test methods & standardization of molecular diagnostics for VRL
  • Management of the Central Molecular Diagnostics Laboratory for the DECODE VRL Study

Memberships & scientific networks:

  • German Society of Pathology (WG Molecular Pathology & Hematopathology)
  • European Association for Hematopathology
  • EuroClonality & National Network for Genomic Medicine Lung Cancer (nNGM)


📍 Institute of Pathology & Neuropathology, Tübingen University Hospital
📧 irina.bonzheim@med.uni-tuebingen.de
📞 +49 7071-29 80218

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